慢性疲労症候群患者の脳は萎縮している

高解像度のstructural 3-T cerebral MRI scanning を26人の CFS患者と26人の年齢、性別を一致させた健常人で行う。 Voxel-wise generalised linear modelling was applied to the processed MR data using permutation-based non-parametric testing, forming clusters at t > 2.3 and testing clusters for significance at p < 0.05, corrected for multiple comparisons across space.結果:ボクセル(p < 0.05, corrected for multiple comparisons)によると CFS群では灰白質の容積が 後頭葉(左右の後頭極; 左側頭後頭葉皮質, 上部; および左supracalcrine皮質), 右角回、左海馬傍回の後部で有意に減少. ボクセルによると (p < 0.05, corrected for multiple comparisons) CFS患者では左後頭葉の白質の容積が有意に減少。

Regional grey and white matter volumetric changes in myalgic encephalomyelitis (chronic fatigue syndrome): a voxel-based morphometry 3-T MRI study.
Puri BK, Jakeman PM, Agour M, Gunatilake KD, Fernando KA, Gurusinghe AI, Treasaden IH, Waldman AD, Gishen P.
Br J Radiol. 2011 Nov 29. [Epub ahead of print]
[PR]

by fibromyalgia11 | 2011-12-02 17:40 | 慢性疲労症候群
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世界標準の線維筋痛症を専門家が説明します


by fibromyalgia11
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