ガバペンは難治性の慢性の咳に有効


8週を超える慢性の難治性の咳患者62 人を無作為にgabepentin (n=32)又は placebo (n=30)に振り分け、10人は研究修了前に中止。 偽薬に比べてGabapentinは有意に咳に特異的な生活の質を改善した(治療期間中のLeicester cough questionnaire scoreの群間の差は1•80, 95% CI 0•56-3•04; p=0•004; number needed to treat of 3•58). Gabapentin群では副作用(大部分は吐き気と疲労)は10人 (31%) に偽薬群では3人 (10%)に生じる.

Lancet. 2012 Aug 27. [Epub ahead of print]
Gabapentin for refractory chronic cough: a randomised, double-blind, placebo-controlled trial.
Ryan NM, Birring SS, Gibson PG.
Priority Centre for Asthma and Respiratory Diseases, School of Medicine and Public Health, The University of Newcastle, Newcastle, NSW, Australia; Department of Respiratory and Sleep Medicine, Hunter Medical Research Institute, John Hunter Hospital, Newcastle, NSW, Australia.
[PR]

by fibromyalgia11 | 2012-09-08 23:03 | 抗痙攣薬
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世界標準の線維筋痛症を専門家が説明します


by fibromyalgia11
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