むずむず脚症候群の安静時の脳のfMRI

方法:安静状態のfMRIsをRLSの投薬を受けていない一次性RLS患者25人と健常者25人で午前中行う。安静状態の連結性を両側の視床 (腹後外側核ventroposterolateral nucleus [VPLN])を伴ったAnalysis of Functional NeuroImages (AFNI) softwareを用いたseed-based法で解析。RLS患者の連結性の特徴を対照群と比較。結果:RLS患者では床と右海馬傍回, 右楔前部, 右中心前回,および両側舌状回の連結性が減少していたが;右上側頭回, 両側中側頭回, および右内側前頭回は視床との連結性が増加。RLSの程度の強さは視床と右海馬傍回の連続性と負の相関(r=-0.414; P=.040).
Sleep Med. 2014 Jan 30. pii: S1389-9457(14)00030-6. doi: 10.1016/j.sleep.2013.09.030. [Epub ahead of print]
Functional connectivity alternation of the thalamus in restless legs syndrome patients during the asymptomatic period: a resting-state connectivity study using functional magnetic resonance imaging.
Ku J1, Cho YW2, Lee YS3, Moon HJ3, Chang H4, Earley CJ5, Allen RP5.
•1Department of Biomedical Engineering, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, South Korea.
•2Department of Neurology, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, South Korea. Electronic address: neurocho@gmail.com.
•3Department of Neurology, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, South Korea.
•4Department of Radiology, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, South Korea.
•5Department of Neurology, Johns Hopkins University, Hopkins Bayview Medical Center, Baltimore, MD, USA.
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by fibromyalgia11 | 2014-02-23 16:13 | むずむず脚症候群
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世界標準の線維筋痛症を専門家が説明します


by fibromyalgia11
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