むずむず脚症候群と冠動脈血流の関連


方法:横断的観察研究で冠動脈造影を受けそれにより様々な冠動脈流量の正常の冠動脈である176人を調べた。本研究には孤立した遅い冠血流(slow coronary flow:SCF)の86人と正常な冠流量(normal coronary flow:NCF)の対照の90人を含める. 冠流量を評価した翌日にthe International Restless Legs Study Group基準に基づいた自己評価のアンケートにより 、RLS評価。以下の質問をした: "Do you have unpleasant leg sensations (like crawling, paraesthesia, or pain) combined with motor restlessness and an urge to move?" The possible responses were as follows: no, less than once/month, 2-4 times/month, 5-14 times/month, and 15 or more times per month. Those who answered that they had these feelings were asked the following two more questions: 1) "Do these symptoms occur only at rest and does moving improve them?" and 2) "Are these symptoms worsen in the evening/at night compared with the
morning?" RLS is considered to be probable if the participant has answered "yes" for all three of the above questions, and has a frequency of ≥5 times/month. Student's t-test, Mann-Whitney U test, multiple logistic regression analysis were used for statistical analysis.結果:RLSは48人で有病率は27%であり年齢と共に有意に有病率は増加。SCFの患者は対照群よりも有意にRLSが多い (p<0.001). RLS患者における年齢で補正したSCFの有病率のオッズは 3.11倍 (95% CI: 1.54-6.29; P<0.001).年齢、性別,BMI, BMI squared, 喫煙などのその他の共変量で補正するとRLSとSCFの有意な関連は実質的には変化しなかった。まとめ:SCFとRLSには強い関連がある。

Anadolu Kardiyol Derg. 2014 Feb 14. doi: 10.5152/akd.2014.5068. [Epub ahead of print]
Association between restless leg syndrom and slow coronary flow.
Erden I1, Cakcak Erden E, Durmuş H, Tıbıllı H, Tabakçı M, Kalkan ME, Türker Y, Akçakoyun M.
•1Clinic of Cardiology, Kartal Koşuyolu Heart and Research Hospital; İstanbul-Turkey.
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by fibromyalgia11 | 2014-07-20 22:10 | むずむず脚症候群
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世界標準の線維筋痛症を専門家が説明します


by fibromyalgia11
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