抗うつ薬による自殺


方法: the Dutch Integrated Primary Care Information (IPCI)データベースによる人口に基づいたコホート研究を行い、1994年から2012年までの抗うつ薬使用者 (n=27,712). Cox proportional hazard モデルを用いて現在のSSRIs, TCAおよびその他の抗うつ薬使用と自殺あるいは自殺企図の関連を調べた。結果:経過観察中, 抗うつ薬使用者の280人が自殺企図または自殺。現在のSSRIs (hazard ratio (HR): 0.78, 95% CI: 0.57-1.07), TCAs (HR: 0.82, 95% CI: 0.48-1.42) およびその他の抗うつ薬 (HR: 0.75, 95% CI: 0.47-1.18) 使用は過去にいずれかの抗うつ薬を使用した者に比べて、有意には自殺に関連しない。
J Affect Disord. 2014 Dec 18;174C:479-484. doi: 10.1016/j.jad.2014.12.032. [Epub ahead of print]
Antidepressant use and the risk of suicide: A population-based cohort study.6請求
Cheung K1, Aarts N2, Noordam R2, van Blijderveen JC3, Sturkenboom MC4, Ruiter R1, Visser LE5, Stricker BH6.
·1Department of Epidemiology, Erasmus MC - University Medical Centre Rotterdam, The Netherlands.
·2Department of Epidemiology, Erasmus MC - University Medical Centre Rotterdam, The Netherlands; Department of Internal Medicine, Erasmus MC - University Medical Centre Rotterdam, The Netherlands.
·3Department of Epidemiology, Erasmus MC - University Medical Centre Rotterdam, The Netherlands; Department of Medical Informatics, Erasmus MC - University Medical Centre Rotterdam, The Netherlands.
·4Department of Medical Informatics, Erasmus MC - University Medical Centre Rotterdam, The Netherlands.
·5Department of Epidemiology, Erasmus MC - University Medical Centre Rotterdam, The Netherlands; Apotheek Haagse Ziekenhuizen - HAGA, The Hague, The Netherlands.
·6Department of Epidemiology, Erasmus MC - University Medical Centre Rotterdam, The Netherlands; Inspectorate of Health Care, The Hague, The Netherlands. Electronic address: b.stricker@erasmusmc.nl
[PR]

by fibromyalgia11 | 2015-01-06 21:20 | 抗うつ薬
line

世界標準の線維筋痛症を専門家が説明します


by fibromyalgia11
line