Q熱疲労症候群と慢性疲労症候群の差


方法:Q熱疲労症候群(Q fever fatigue syndrome:QFS) (n=117) およびCFS (n=173)の二つの独立した前向き研究のデータを各々統合し解析。結果:QFSは女性が少なく、BMIが高く, 症状発生前に抑うつの治療を受けることが少ない。症状の期間で調整し、機能障害のレベルと追加的な症状の存在に関するQFS およびCFSの診断基準の差を是正した後, 女性の割合とBMIの差は有意なまま.修正後, QFS患者は有意に高齢. すべての解析で、QFS 患者はCFS患者と同程度に疲労しており苦悩していたが, 追加的な症状は少なかった. QFS患者はより強い身体的な特性を持っており, 身体活動のレベルが高い。炎症マーカーやその他の疲労に関連した認知行動の変数に関しては差がなかった。以前 CFSで確立された, 認知行動の変数と疲労の関係はQFS患者では、身体活動と疲労の逆関連を除けば、確かめられなかった。
J Psychosom Res. 2015 Jul 17. pii: S0022-3999(15)00492-4. doi: 10.1016/j.jpsychores.2015.07.005. [Epub ahead of print]
A comparison of patients with Q fever fatigue syndrome and patients with chronic fatigue syndrome with a focus on inflammatory markers and possible fatigue perpetuating cognitions and behaviour.
Keijmel SP1, Saxe J2, van der Meer JW3, Nikolaus S4, Netea MG5, Bleijenberg G6, Bleeker-Rovers CP7, Knoop H8.
•1Radboud Expertise Centre for Q fever, Department of Internal Medicine, Division of Infectious Diseases, Radboud university medical center, Nijmegen, The Netherlands; Department of Internal Medicine, Division of Infectious Diseases, Radboud university medical center, Nijmegen, The Netherlands; Expert Centre for Chronic Fatigue, Radboud university medical center, Nijmegen, The Netherlands. Electronic address: Stephan.Keijmel@radboudumc.nl.
•2Radboud Expertise Centre for Q fever, Department of Internal Medicine, Division of Infectious Diseases, Radboud university medical center, Nijmegen, The Netherlands; Department of Internal Medicine, Division of Infectious Diseases, Radboud university medical center, Nijmegen, The Netherlands. Electronic address: j_saxe@gmx.de.
•3Department of Internal Medicine, Division of Infectious Diseases, Radboud university medical center, Nijmegen, The Netherlands. Electronic address: Jos.vanderMeer@radboudumc.nl.
•4Expert Centre for Chronic Fatigue, Radboud university medical center, Nijmegen, The Netherlands. Electronic address: Stephanie.Nikolaus@radboudumc.nl.
•5Department of Internal Medicine, Division of Infectious Diseases, Radboud university medical center, Nijmegen, The Netherlands. Electronic address: Mihai.Netea@radboudumc.nl.
•6Expert Centre for Chronic Fatigue, Radboud university medical center, Nijmegen, The Netherlands. Electronic address: Gijs.Bleijenberg@radboudumc.nl.
•7Radboud Expertise Centre for Q fever, Department of Internal Medicine, Division of Infectious Diseases, Radboud university medical center, Nijmegen, The Netherlands; Department of Internal Medicine, Division of Infectious Diseases, Radboud university medical center, Nijmegen, The Netherlands. Electronic address: Chantal.Bleeker-Rovers@radboudumc.nl.
•8Expert Centre for Chronic Fatigue, Radboud university medical center, Nijmegen, The Netherlands. Electronic address: Hans.Knoop@radboudumc.nl.
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by fibromyalgia11 | 2015-08-17 19:12 | 慢性疲労症候群
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