むずむず脚症候群の疫学(有病率、危険因子など)
方法:2015年5月から2016年6月まで、13,448人の献血者をthe Danish Blood Donor Studyに登録.有効なCambridge-HopkinsRLS-アンケートを用いてRLSを同定.アンケートと人口登録を用いて集めた社会的に関連のあるデータとRLSの関連を評価するために、ロジスティック回帰を用いた。結果:本研究で、女性の7.2% と男性の4.5%がRLSと分類. RLSは以下と関連:女性、高齢、喫煙、頻繁のアルコール消費、および低い教育。RLSに関連した症状は、女性の中では肥満、出産回数および含める前の3年間の献血の強度に関連。RLSは以下と関連せず:決勝フェリチンの低下、就労状態、および収入。
SleepMed. 2017 Aug;36:55-61. doi: 10.1016/j.sleep.2017.04.014. Epub2017 May 26.
Prevalence of restlesslegs syndrome and associated factors in an otherwise healthy population:results from the Danish Blood Donor Study.
DidriksenM1, Rigas AS1, Allen RP2, BurchellBJ3, DiAngelantonio E4, NielsenMH1, Jennum P5, Werge T6, ErikstrupC7, PedersenOB8, Bruun MT9, BurgdorfKS1, SørensenE1, Ullum H10.
1
Departmentof Clinical Immunology, Copenhagen University Hospital, Rigshospitalet,Copenhagen, Denmark.
2
Department ofNeurology, John Hopkins University School of Medicine, Baltimore, MD, USA.
3
Faculty ofSocial and Political Sciences, University of Cambridge, Cambridge, UK.
4
Departmentof Public Health and Primary Care, University of Cambridge, Cambridge, UK;Institute for Health Research, University of Cambridge, Blood and TransplantResearch Unit in Donor Health and Genomics Cambridge, UK.
5
Departmentof Clinical Neurophysiology, Danish Center for Sleep Medicine, Glostrup,Denmark; Faculty of Health, University of Copenhagen, Copenhagen, Denmark.
6
Institute ofBiological Psychiatry, Mental Health Centre Sct. Hans, Mental Health Services,Copenhagen, Denmark; Department of Clinical Medicine, University of Copenhagen,Copenhagen, Denmark; IPSYCH, The Lundbeck Foundation Initiative for IntegrativePsychiatric Research, Copenhagen, Denmark.
7
Departmentof Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.
8
Departmentof Clinical Immunology, Nastved Sygehus, Nastved, Denmark.
9
Departmentof Clinical Immunology, Odense University Hospital, Odense, Denmark.
10
Departmentof Clinical Immunology, Copenhagen University Hospital, Rigshospitalet,Copenhagen, Denmark. Electronic address: henrik.ullum@regionh.dk.